https://fscimage.fishersci.com/msds/45409.htm Material Safety Data Sheet Ethyl alcohol, Denatured, 190 Proof (S73985) ACC# 45409 Section 1 - Chemical Product and Company Identification MSDS Name: Ethyl alcohol, Denatured, 190 Proof (S73985) Catalog Numbers: S73979, S739791, S739792, S73985, S739851, S739852, S739853, S739854, S93232 Synonyms: Denatured Alcohol; Ethanol; Grain Alcohol. Company Identification: Fisher Scientific 1 Reagent Lane Fair Lawn, NJ 07410 For information, call: 201-796-7100 Emergency Number: 201-796-7100 For CHEMTREC assistance, call: 800-424-9300 For International CHEMTREC assistance, call: 703-527-3887 Section 2 - Composition, Information on Ingredients CAS# Chemical Name Percent EINECS/ELINCS 64-17-5 Ethyl alcohol 85 200-578-6 67-63-0 Isopropyl alcohol 6.4 200-661-7 7732-18-5 Water 5.0 231-791-2 67-56-1 Methyl alcohol 2.9 200-659-6 108-10-1 Methylisobutyl ketone 0.7 203-550-1 Section 3 - Hazards Identification EMERGENCY OVERVIEW Appearance: colorless liquid. Flash Point: 41 deg F. Danger! Causes severe eye irritation. Causes respiratory tract irritation. Flammable liquid and vapor. This substance has caused adverse reproductive and fetal effects in humans. May be absorbed through intact skin. May cause central nervous system depression. May cause blindness if swallowed. May cause liver and kidney damage. Causes moderate skin irritation. Target Organs: Blood, kidneys, central nervous system, liver, eyes.
Potential Health Effects Eye: Causes severe eye irritation. May cause painful sensitization to light. May cause chemical conjunctivitis and corneal damage. Skin: Causes moderate skin irritation. May be absorbed through the skin. May cause cyanosis of the extremities. Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause systemic toxicity with acidosis. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure. May cause blindness. Inhalation: Inhalation of high concentrations may cause central nervous system effects characterized by nausea, headache, dizziness, unconsciousness and coma. Causes respiratory tract irritation. May cause narcotic effects in high concentration. Vapors may cause dizziness or suffocation. Chronic: Prolonged or repeated skin contact may cause defatting and dermatitis. May cause liver and kidney damage. May cause reproductive and fetal effects. Laboratory experiments have resulted in mutagenic effects. Animal studies have reported the development of tumors. Section 4 - First Aid Measures
https://fscimage.fishersci.com/msds/45409.htm (1 of 7)9/19/2005 10:57:18 AM https://fscimage.fishersci.com/msds/45409.htm Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Ingestion: Call a poison control center. If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical aid. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Treat symptomatically and supportively. Persons with skin or eye disorders or liver, kidney, chronic respiratory diseases, or central and peripheral nervous sytem diseases may be at increased risk from exposure to this substance. Activated charcoal does not reduce ethanol absorption. Antidote: Ethanol may inhibit methanol metabolism. Section 5 - Fire Fighting Measures

General Information: Containers can build up pressure if exposed to heat and/or fire. As in any fire, wear a self- contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors can travel to a source of ignition and flash back. May burn with invisible flame. Will burn if involved in a fire. Flammable Liquid. Can release vapors that form explosive mixtures at temperatures above the flashpoint. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. May be ignited by heat, sparks, and flame. Vapors may form an explosive mixture with air. Extinguishing Media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective. For large fires, use water spray, fog or alcohol-resistant foam. Do NOT use straight streams of water. For small fires, use carbon dioxide, dry chemical, dry sand, or alcohol-resistant foam. Cool containers with flooding quantities of water until well after fire is out. Flash Point: 41e deg F ( 5.00 deg C) Autoignition Temperature: 752 deg F ( 400.00 deg C) Explosion Limits, Lower:4 vol % Upper: 20 vol % NFPA Rating: (estimated) Health: 2; Flammability: 3; Instability: 0 Section 6 - Accidental Release Measures

General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors. Water spray may reduce vapor but may not prevent ignition in closed spaces. Section 7 - Handling and Storage

Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well- ventilated area. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Keep away from heat, sparks and flame. Do not ingest or inhale. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Storage: Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area. Do not store near perchlorates, peroxides, chromic acid or nitric acid. Section 8 - Exposure Controls, Personal Protection

Engineering Controls: Use explosion-proof ventilation equipment. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep https://fscimage.fishersci.com/msds/45409.htm (2 of 7)9/19/2005 10:57:18 AM https://fscimage.fishersci.com/msds/45409.htm airborne concentrations below the permissible exposure limits. Exposure Limits Chemical Name ACGIH NIOSH OSHA - Final PELs Ethyl alcohol 1000 ppm TWA 1000 ppm TWA; 1900 mg/m3 TWA 3300 ppm IDLH 1000 ppm TWA; 1900 mg/m3 TWA Isopropyl alcohol 200 ppm TWA; 400 ppm STEL 400 ppm TWA; 980 mg/m3 TWA 2000 ppm IDLH 400 ppm TWA; 980 mg/m3 TWA Water none listed none listed none listed Methyl alcohol 200 ppm TWA; 250 ppm STEL; Skin - potential significant contribution to overall exposure by the cutaneous r oute 200 ppm TWA; 260 mg/m3 TWA 6000 ppm IDLH 200 ppm TWA; 260 mg/m3 TWA Methylisobutyl ketone 50 ppm TWA; 75 ppm STEL 50 ppm TWA; 205 mg/m3 TWA 500 ppm IDLH 100 ppm TWA; 410 mg/m3 TWA
OSHA Vacated PELs: Ethyl alcohol: 1000 ppm TWA; 1900 mg/m3 TWA Isopropyl alcohol: 400 ppm TWA; 980 mg/ m3 TWA Water: No OSHA Vacated PELs are listed for this chemical. Methyl alcohol: 200 ppm TWA; 260 mg/m3 TWA Methylisobutyl ketone: 50 ppm TWA; 205 mg/m3 TWA Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use. Section 9 - Physical and Chemical Properties

Physical State: Liquid Appearance: colorless Odor: alcohol-like pH: Not available. Vapor Pressure: 42 mm Hg Vapor Density: 1.6 Evaporation Rate:4.1 Viscosity: Not available. Boiling Point: 74-80 deg C Freezing/Melting Point:-80 deg C Decomposition Temperature:Not available. Solubility: Soluble in water. Specific Gravity/Density:0.795 Molecular Formula:CH3CH2OH Molecular Weight:46.0414 Section 10 - Stability and Reactivity

Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: High temperatures, high temperatures, incompatible materials, ignition sources, excess heat, strong oxidants, oxidizers. Incompatibilities with Other Materials: Strong oxidizing agents, peroxides, acids, acid chlorides, acid anhydrides, alkali metals, ammonia, permanganic acid, ruthenium (VIII) oxide, bromine pentafluoride, nitrosyl perchlorate, chromyl chloride, uranium hexafluoride, iodine heptafluoride, uranyl perchlorate, acetyl bromide, silver nitrate, disulfuryl difluoride, magnesium perchlorate, platinum, potassium-tert-butoxide, silver oxide, hydrazine, tetrachlorosilane + water, acetyl chloride, calcium hypochlorite, mercuric nitrate, perchloric acid, potassium dioxide, sodium, chlorosulfonic acid, 2-chloromethyl furan, oleum, lithium aluminum hydride. Hazardous Decomposition Products: Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide. Hazardous Polymerization: Will not occur. Section 11 - Toxicological Information https://fscimage.fishersci.com/msds/45409.htm (3 of 7)9/19/2005 10:57:18 AM https://fscimage.fishersci.com/msds/45409.htm

RTECS#: CAS# 64-17-5: KQ6300000 CAS# 67-63-0: NT8050000 CAS# 7732-18-5: ZC0110000 CAS# 67-56-1: PC1400000 CAS# 108-10-1: SA9275000 LD50/LC50: CAS# 64-17-5: Draize test, rabbit, eye: 500 mg Severe; Draize test, rabbit, eye: 500 mg/24H Mild; Draize test, rabbit, skin: 20 mg/24H Moderate; Inhalation, mouse: LC50 = 39 gm/m3/4H; Inhalation, rat: LC50 = 20000 ppm/10H; Oral, mouse: LD50 = 3450 mg/kg; Oral, rabbit: LD50 = 6300 mg/kg; Oral, rat: LD50 = 7060 mg/kg; Oral, rat: LD50 = 9000 mg/kg; CAS# 67-63-0: Draize test, rabbit, eye: 100 mg Severe; Draize test, rabbit, eye: 10 mg Moderate; Draize test, rabbit, eye: 100 mg/24H Moderate; Draize test, rabbit, skin: 500 mg Mild; Inhalation, mouse: LC50 = 53000 mg/m3; Inhalation, rat: LC50 = 16000 ppm/8H; Inhalation, rat: LC50 = 72600 mg/m3; Oral, mouse: LD50 = 3600 mg/kg; Oral, mouse: LD50 = 3600 mg/kg; Oral, rabbit: LD50 = 6410 mg/kg; Oral, rat: LD50 = 5045 mg/kg; Oral, rat: LD50 = 5000 mg/kg; Skin, rabbit: LD50 = 12800 CAS# 7732-18-5: Oral, rat: LD50 = >90 mL/kg; CAS# 67-56-1: Draize test, rabbit, eye: 40 mg Moderate; Draize test, rabbit, eye: 100 mg/24H Moderate; Draize test, rabbit, skin: 20 mg/24H Moderate; Inhalation, rabbit: LC50 = 81000 mg/m3/14H; Inhalation, rat: LC50 = 64000 ppm/4H; Oral, mouse: LD50 = 7300 mg/kg; Oral, rabbit: LD50 = 14200 mg/kg; Oral, rat: LD50 = 5600 mg/kg; Skin, rabbit: LD50 = 15800 mg/kg; CAS# 108-10-1: Draize test, rabbit, eye: 40 mg Severe; Draize test, rabbit, eye: 100 uL/24H Moderate; Draize test, rabbit, skin: 500 mg/24H Mild; Inhalation, mouse: LC50 = 23300 mg/m3; Inhalation, mouse: LC50 = 23300 mg/m3; Inhalation, rat: LC50 = 100 gm/m3; Oral, mouse: LD50 = 1900 mg/kg; Oral, mouse: LD50 = 2850 mg/kg; Oral, rat: LD50 = 2080 mg/kg; Oral, rat: LD50 = 4600 mg/kg; Carcinogenicity: CAS# 64-17-5: Not listed by ACGIH, IARC, NTP, or CA Prop 65. CAS# 67-63-0: Not listed by ACGIH, IARC, NTP, or CA Prop 65. CAS# 7732-18-5: Not listed by ACGIH, IARC, NTP, or CA Prop 65. CAS# 67-56-1: Not listed by ACGIH, IARC, NTP, or CA Prop 65. CAS# 108-10-1: Not listed by ACGIH, IARC, NTP, or CA Prop 65.
Epidemiology: Methanol has been shown to produce fetotoxicity in the embryo or fetus of laboratory animals. Specific developmental abnormalities include cardiovascular, musculoskeletal, and urogenital systems.Prenatal https://fscimage.fishersci.com/msds/45409.htm (4 of 7)9/19/2005 10:57:18 AM https://fscimage.fishersci.com/msds/45409.htm exposure to ethanol is associated with a distinct pattern of congenital malformations that have collectively been termed the "fetal alcohol syndrome".Ethanol has been shown to produce fetotoxicity in the embryo or fetus of laboratory animals. Teratogenicity: CAS# 64-17-5: Oral, Human - woman: TDLo = 41 gm/kg (female 41 week(s) after conception) Effects on Newborn - Apgar score (human only) and Effects on Newborn - other neonatal measures or effects and Effects on Newborn - drug dependence. Reproductive Effects: CAS# 64-17-5: Intrauterine, Human - woman: TDLo = 200 mg/kg (female 5 day(s) pre- mating) Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated). Mutagenicity: CAS# 64-17-5: DNA Inhibition: Human, Lymphocyte = 220 mmol/L.; Cytogenetic Analysis: Human, Lymphocyte = 1160 gm/L.; Cytogenetic Analysis: Human, Fibroblast = 12000 ppm.; Cytogenetic Analysis: Human, Leukocyte = 1 pph/72H (Continuous).; Sister Chromatid Exchange: Human, Lymphocyte = 500 ppm/72H (Continuous). Neurotoxicity: No information found. Other Studies: Section 12 - Ecological Information

Ecotoxicity: Fish: Rainbow trout: LC50 = 12900-15300 mg/L; 96 Hr; Flow-through @ 24-24.3